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The Death from Fatal Familial Insomnia

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Updated on: 2017-11-22

Fatal Familial Insomnia is caused by a rare autosomal dominant prion disease which is inherited. This is a disaese of the brain and a very rare in occurrence. Only 50 families all over the world bear this
dominant gene. The complete sleeplessness due to this disease is untreatable and ultimately leads to death. If one parent of the offspring bears this gene, then the offspring will inherit it in 50% cases. The patients of Fatal Familial Insomnia has neural degeneration which leads to long-term death.

Inspite of increased food intake the patients tend to lose weight, thyroid hormone starts declining, elevated sympathetic activation takes place and the resistance of the body to infection becomes poor.
No tratment as such has been invented for FFI. Gene therapy has been unsuccessful so far though hope rests on that. For sleeplessness the effect of Sleeping pills have not been helpful. If treatment can be done focussing upon the symptoms, then the patients can lead an improved life.



 
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